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Glyphosate-based herbicides have been extensively used in agriculture, mainly due to the prevalence of genetically modified, glyphosate-resistant food crops.    However, the widespread use of glyphosate has led to its detection and prevalence in water, soils, food crops, and even human urine, raising flags about its potential effects on human health. Recent studies have linked...

The Impact of Delivery Mode and Feeding Method on Infant Gut Microbiome Establishment

Special thanks to Eray Şahin for the bioinformatics analysis of data. This guide will discuss the impact of delivery mode and feeding method on infant gut microbiome establishment, a study conducted by researchers from the University of California Davis.   The research team used CosmosID’s platform to analyze microbial samples collected from infants born vaginally...

Background Chronic kidney disease is a leading cause of morbidity and mortality around the globe. The disease often leads to kidney failure whe it progresses to end-stage renal disease (ESRD). ESRD produces $34 billion of costs annually to the US economy.  ESRD etiology is often driven by the accumulation of toxic metabolites in body compartments....

Background Metagenomics studies using shotgun sequencing have been an important tool for investigating the gut microbiome of pets, including dogs, in recent years.   These studies involve sequencing all DNA fragments present in a sample, allowing for the identification and characterization of the diverse range of microorganisms present in the gut microbiome. Such studies have...

Approximately 85%–90% of individuals develop acne during adolescence, a time period that coincides with the onset and transition through puberty.  It is well established that the physical and biochemical properties of the skin are influenced by puberty and skin colonization by microbes. Functional genes encoded in the microbes may alter skin ecology as well. In...

In metagenomics, biological specimens are sometimes collected from host tissue that contains a high ratio of host to bacterial DNA. When shotgun metagenomics sequencing data are generated for these specimens, they normally contain a large fraction of host reads compared to microbial reads. Analyzing microbiome data with a high host ratio of reads can lead...

A complete analysis of the microbiome should combine taxonomic profiling with functional characterization to discover the full potential of an entire community of microorganisms. However, research teams often require specialized training and extensive computational infrastructure to establish an in-house suite of tools for processing shotgun metagenomic data – and even with the right know-how, the...

Thank you for your interest in our series of vaginal microbiome comparisons. Based on the results of this month’s survey, today we follow up on the functional metagenomic diversity of the non-pregnant community state type (CST) I female vaginal microbiome. As a quick refresher, a healthy vaginal microbiome harbors low microbial diversity, as opposed to...

We are pleased to announce the 2022 CosmosID North & South America Grant Program Winners! We are awarding a group of three scientists with funding and resources along their journey in the microbiome space. The winners are each receiving 90 samples extracted and sequenced, taxonomic profiling, functional profiling, statistical comparative analysis & a CosmosID-HUB bronze subscription! Each...

Congratulations to our three 2022 Grant Program for Scientists & Start-Ups North and South America winners! We are awarding a group of scientists with funding and resources along their journey in the microbiome space. The winners are receiving 90 samples extracted and sequenced, taxonomic profiling, functional profiling, statistical comparative analysis & a CosmosID-HUB bronze subscription! The...