CosmosID offers end-to-end whole genome sequencing (WGS) and analysis of microbial isolates. DNA Extraction, Library preparation and Next-Generation Sequencing (NGS) is carried out in our CLIA-certified facilities. For data interpretation we use an in-house bioinformatics platform that is built around CosmosID’s class-leading databases and has been optimized for isolate whole genome data.
WGS of bacterial isolates offers unique advantages over traditional typing methods and is now available at very affordable rates. Unlike PCR, this affordable technology reveals the complete genetic makeup of an organism and offers unprecedented insight. A single assay reveals:
There are numerous applications of WGS of isolates, given the ability to reveal detailed taxonomic, phylogentic and functional output. CosmosID has extensive experience in:
Customize your isolate sequencing:
Then mail us your isolate cell pellets or nucleic acid!
Sample Processing at CosmosID’s CLIA certified and GCP Laboratory.
We support a range of academic and industrial applications including, but not limited to, probiotic/LBP strain characterization, epidemiology, infectious disease research, food safety testing, manufacturing QC and many others!
We offer a range of different turnaround time options to suit your project needs with sequencing and analysis being as fast as 3-5 business days.
Bacterial and fungal organisms differ tremendously based on their cell wall thickness, genome size & GC content. As such, some organisms require a slightly more specialized approach when it comes to DNA extraction, library preparation techniques, targeted coverage and analysis strategy. Once we receive a list of your organisms of interest, we’ll assess these nuances and get back to you with a proposed plan of action. Nonetheless, by assembling genomes de novo, this is well suited to novel strain discovery in a wide range of applications.