Sequencing ServicesBacterial Isolate Sequencing

CosmosID offers end-to-end whole genome sequencing (WGS) and analysis of microbial isolates. DNA Extraction, Library preparation and Next-Generation Sequencing (NGS) is carried out in our CLIA-certified facilities. For data interpretation we use an in-house bioinformatics platform that is built around CosmosID’s class-leading databases and has been optimized for isolate whole genome data.

WGS of bacterial isolates offers unique advantages over traditional typing methods and is now available at very affordable rates. Unlike PCR, this affordable technology reveals the complete genetic makeup of an organism and offers unprecedented insight. A single assay reveals:

• Unambiguous taxonomic classification
• Highly accurate depiction of strain relatedness, pathogenesis and transmission
• Functional characteristics like antimicrobial resistance, virulence, and metabolic capabilities

There are numerous applications of WGS of isolates, given the ability to reveal detailed taxonomic, phylogentic and functional output. CosmosID has extensive experience in:

• Live Biotherapeutic & Probiotic Characterization
• Hospital-Acquired Infections (HAI’s) & Clinical Microbiology
• Strain Sub-Typing & Epidemiology
• Food Safety Testing
• Agricultural & Environmental Research
• Academic Research

• Raw data via AWS Transfer
• Data QC, Genome Assembly, Strain ID, SNP Analysis & Phylogenetic Trees
• CosmosID Analysis Report
• Data consultation & walk-through
• Characterization – AMR, Virulence, MLST, Average Nucleotide Identity & Functional Annotation
• Custom Bioinformatics available on request

Customize your isolate sequencing:

1. Choose your sequencing technology – Short & Long-Reads available.
2. Choose your turnaround time – As fast as 3 days.
3. Highlight your bioinformatics & reporting requirements.

Then mail us your isolate cell pellets or nucleic acid!

Sample Processing at CosmosID’s CLIA certified and GCP Laboratory.