Chronic fatigue syndrome (CFS) is a burden on healthcare and remains a poorly understood disorder that affects millions of people worldwide. While the exact cause of CFS remains unknown, recent research has suggested that the gut microbiome may have a role in the development and progression of the disease. In this guide, we...
To evaluate the impact of ports on the biodiversity in their vicinity, a recent study collected coral reef sediment samples from the vicinity of Port Everglades in South Florida, and performed 16S rRNA sequencing on the samples. CosmosID analyzed the 16S rRNA gene-based microbiome community data to illustrate the impact of port activities...
Until recently, there has been a gap in information about the temporal changes of the gut microbiome associated with malaria infection. To fill that gap, a recent study– where shotgun sequences were analyzed by the CosmosID-HUB Microbiome Platform – used 16S rRNA and shotgun sequencing to analyze the rectal samples from experimentally malaria-infected macaques...
Obesity prevalence has been skyrocketing since the 1970s globally, with the Eastern Mediterranean region being no exception. For instance, obesity is prevalent in 20% of Saudi Arabian adults, with an elevated prevalence in females. The increase of obesity rates in adult females of reproductive age is particularly worrying, given new evidence suggesting links between...
The gut microbiome hosts many different microorganisms. There are more bacteria in the human gut than the stars in the Milky Way… From bacteria, to viruses and eukaryotes, these microbes are key players in the etiology of a number of diseases, such as cancer, depression, and diabetes. These microbes may even influence the host...
In metagenomics, biological specimens are sometimes collected from host tissue that contains a high ratio of host to bacterial DNA. When shotgun metagenomics sequencing data are generated for these specimens, they normally contain a large fraction of host reads compared to microbial reads. Analyzing microbiome data with a high host ratio of reads can lead...
A complete analysis of the microbiome should combine taxonomic profiling with functional characterization to discover the full potential of an entire community of microorganisms. However, research teams often require specialized training and extensive computational infrastructure to establish an in-house suite of tools for processing shotgun metagenomic data – and even with the right know-how, the...
The gut microbiome has clear implications for health and disease. Recent evidence of this comes from a US FDA vote for approval of the microbiome-based drug RBX2660, created by Rebiotix Inc, A Ferring Company, to treat potentially deadly bacterial infections with Clostridium difficile (Cdiff). Cdiff is a common gut bacteria that may cause severe diarrhea...
Multiple sclerosis (MS) is an autoimmune neurodegenerative disease targeting the central nervous system with a prevalence of around 2.8 million people globally. The etiopathogenesis of MS is multifactorial and involves environmental factors. Amongst the environmental factors, the gut microbiota is a key player modulating MS. Dietary habits drive the gut microbiome. Thus, dietary shifts change...
We are pleased to announce the 2022 CosmosID North & South America Grant Program Winners! We are awarding a group of three scientists with funding and resources along their journey in the microbiome space. The winners are each receiving 90 samples extracted and sequenced, taxonomic profiling, functional profiling, statistical comparative analysis & a CosmosID-HUB bronze subscription! Each...
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