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Advancements in biological and biomedical research are fueled by the analysis of vast, complex, integrated datasets, made possible through large-scale computational resources.   While bioinformatics has revolutionized our understanding of diseases such as cancer or COVID-19, there are costs associated with the computing requirements. On one hand, computational power requires financial process, but it may...

The field of microbiome-based therapeutics is flourishing. The recent approval of Seres Therapeutics’ drug, Vowst, against C. difficile infections has spearheaded the interest in microbiome-based therapeutics.    The recent development of microbiome-based therapeutics may have contributed to a rising trend of reclassifying microbiome probiotics as pharmaceuticals. The European Union (EU) is witnessing significant progress in...

Glyphosate-based herbicides have been extensively used in agriculture, mainly due to the prevalence of genetically modified, glyphosate-resistant food crops.    However, the widespread use of glyphosate has led to its detection and prevalence in water, soils, food crops, and even human urine, raising flags about its potential effects on human health. Recent studies have linked...

The Impact of Delivery Mode and Feeding Method on Infant Gut Microbiome Establishment

Special thanks to Eray Şahin for the bioinformatics analysis of data. This guide will discuss the impact of delivery mode and feeding method on infant gut microbiome establishment, a study conducted by researchers from the University of California Davis.   The research team used The CosmosID Metagenomics App to analyze microbial samples collected from infants...

New research has found a way to predict the impact of prebiotics on the human gut microbiota within days, using an ex vivo, reactor-based, high-throughput SIFR® (Systemic Intestinal Fermentation Research) technology.    In this article, we’ll take a closer look at the research, its method, and what it means for the future of prebiotic research....

Prebiotics are non-digestible food ingredients that selectively promote the growth and activity of beneficial gut microbiota, thus conferring health benefits to the host. Human milk oligosaccharides (HMOs) are prebiotics that are present in human milk and selectively stimulate the growth of bifidobacteria in infants.    A new study has investigated the effects of HMOs in...

Key Metagenomics Techniques & Their Uses

Welcome to the exciting world of metagenomics! Metagenomics is a powerful tool that allows us to study complex microbial communities in their natural environments. It has revolutionized our understanding of how microbes interact with each other and their environment, and it can help us better understand many aspects of biology, from disease diagnosis to climate...