In metagenomics, biological specimens are sometimes collected from host tissue that contains a high ratio of host to bacterial DNA. When shotgun metagenomics sequencing data are generated for these specimens, they normally contain a large fraction of host reads compared to microbial reads. Analyzing microbiome data with a high host ratio of reads can lead...
A complete analysis of the microbiome should combine taxonomic profiling with functional characterization to discover the full potential of an entire community of microorganisms. However, research teams often require specialized training and extensive computational infrastructure to establish an in-house suite of tools for processing shotgun metagenomic data – and even with the right know-how, the...
The gut microbiome has clear implications for health and disease. Recent evidence of this comes from a US FDA vote for approval of the microbiome-based drug RBX2660, created by Rebiotix Inc, A Ferring Company, to treat potentially deadly bacterial infections with Clostridium difficile (Cdiff). Cdiff is a common gut bacteria that may cause severe diarrhea...
Multiple sclerosis (MS) is an autoimmune neurodegenerative disease targeting the central nervous system with a prevalence of around 2.8 million people globally. The etiopathogenesis of MS is multifactorial and involves environmental factors. Amongst the environmental factors, the gut microbiota is a key player modulating MS. Dietary habits drive the gut microbiome. Thus, dietary shifts change...
We are pleased to announce the 2022 CosmosID North & South America Grant Program Winners! We are awarding a group of three scientists with funding and resources along their journey in the microbiome space. The winners are each receiving 90 samples extracted and sequenced, taxonomic profiling, functional profiling, statistical comparative analysis & a CosmosID-HUB bronze subscription! Each...
Congratulations to our three 2022 Grant Program for Scientists & Start-Ups North and South America winners! We are awarding a group of scientists with funding and resources along their journey in the microbiome space. The winners are receiving 90 samples extracted and sequenced, taxonomic profiling, functional profiling, statistical comparative analysis & a CosmosID-HUB bronze subscription! The...
Congratulations to our three 2022 Grant Program for Scientists & Start-Ups North and South America winners! We are awarding a group of scientists with funding and resources along their journey in the microbiome space. The winners are receiving 90 samples extracted and sequenced, taxonomic profiling, functional profiling, statistical comparative analysis & The Metagenomics App bronze...
Congratulations to our three 2022 Grant Program for Scientists & Start-Ups North and South America winners! We are awarding a group of scientists with funding and resources along their journey in the microbiome space. The winners are receiving 90 samples extracted and sequenced, taxonomic profiling, functional profiling, statistical comparative analysis & a CosmosID-HUB bronze subscription! The...
A recent article featured on BBC highlights that the gut microbiome may have a greater role in the improvement of health through exercise than we previously thought. Our guts are alive with a vast diversity of microbial residents. Their roles range from fermenting dietary fibers, vitamin synthesis, and fat metabolism regulation to immune support against...
Nasal swabs and saliva are conventional methods for detection of SARS-CoV-2, but the virus is also present in feces. Therefore, fecal material in wastewater samples could be used to track community dynamics of the virus. To do that, Brumfield et al. (2022) collected wastewater samples from manholes and then processed them for microbial genome sequencing...
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