Whole-genome sequencing using NGS technology provides comprehensive genetic analysis of the entire metagenome.
Whole genome sequencing (WGS) is a comprehensive method for analyzing the entire metagenome. Whole genome sequencing is a powerful tool for microbiome research and has been instrumental in identifying crucial taxonomic and functional information. Not only can it differentiate one microbiome from another, in ways previously underappreciated, but also its impact on its surrounding environment, whether that be the human gut, soil, foods and many other environments of interest.
Though the sequencing methods are commonly associated with sequencing human genomes, the scalability and flexibility of next generation sequencing (NGS) technology has made it equally useful for the whole genome sequencing of livestock, plants, or disease-related microbes.