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In metagenomics, biological specimens are sometimes collected from host tissue that contains a high ratio of host to bacterial DNA. When shotgun metagenomics sequencing data are generated for these specimens, they normally contain a large fraction of host reads compared to microbial reads. Analyzing microbiome data with a high host ratio of reads can lead...

A complete analysis of the microbiome should combine taxonomic profiling with functional characterization to discover the full potential of an entire community of microorganisms. However, research teams often require specialized training and extensive computational infrastructure to establish an in-house suite of tools for processing shotgun metagenomic data – and even with the right know-how, the...

Obesity is a health problem that increases mortality and morbidity globally. Although there have been developments in therapeutic obesity treatments, the prevalence of obesity has increased. Additionally, there have been developments in understanding the mechanisms underlying obesity. For example, recent evidence highlights the gut microbiota as a risk factor for obesity. However, there is limited...

Thank you for your interest in our series of vaginal microbiome comparisons. Based on the results of this month’s survey, today we follow up on the functional metagenomic diversity of the non-pregnant community state type (CST) I female vaginal microbiome. As a quick refresher, a healthy vaginal microbiome harbors low microbial diversity, as opposed to...

We are pleased to announce the 2022 CosmosID North & South America Grant Program Winners! We are awarding a group of three scientists with funding and resources along their journey in the microbiome space. The winners are each receiving 90 samples extracted and sequenced, taxonomic profiling, functional profiling, statistical comparative analysis & a CosmosID-HUB bronze subscription! Each...

Congratulations to our three 2022 Grant Program for Scientists & Start-Ups North and South America winners! We are awarding a group of scientists with funding and resources along their journey in the microbiome space. The winners are receiving 90 samples extracted and sequenced, taxonomic profiling, functional profiling, statistical comparative analysis & a CosmosID-HUB bronze subscription! The...

Congratulations to our three 2022 Grant Program for Scientists & Start-Ups North and South America winners! We are awarding a group of scientists with funding and resources along their journey in the microbiome space. The winners are receiving 90 samples extracted and sequenced, taxonomic profiling, functional profiling, statistical comparative analysis & a CosmosID-HUB bronze subscription! The...

Congratulations to our three 2022 Grant Program for Scientists & Start-Ups North and South America winners! We are awarding a group of scientists with funding and resources along their journey in the microbiome space. The winners are receiving 90 samples extracted and sequenced, taxonomic profiling, functional profiling, statistical comparative analysis & a CosmosID-HUB bronze subscription! The...

Nasal swabs and saliva are conventional methods for detection of SARS-CoV-2, but the virus is also present in feces. Therefore, fecal material in wastewater samples could be used to track community dynamics of the virus. To do that, Brumfield et al. (2022) collected wastewater samples from manholes and then processed them for microbial genome sequencing...

The skin is the body’s first line of defense, protecting the host against environmental or microbial insults by the imposition of a physical barrier. Upon microbial entry into wounds, innate immune cells generate antimicrobial proteins to prevent bacterial infections. A well-studied example is the innate immune circuits of IL-17 and IL-22, which are activated by...